Dr Rahul Bhargava Haematologist

MBBS, MD, DM (Clinical Haematology)

Principal Director & Chief Hematology at Fortis Hospital

MBBS, MD, DM (Clinical Haematology)

Principal Director & Chief Hematology at Fortis Hospital

Acute Myelogenous Leukemia

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Frequently Asked Questions (FAQ) :

The chemotherapy regimen often includes an induction phase to achieve remission and a consolidation phase to eliminate remaining leukemia cells. Common drugs include cytarabine and anthracyclines like daunorubicin or idarubicin.

Induction therapy aims to induce remission by killing as many leukemia cells as possible. This typically involves intensive chemotherapy.

Consolidation therapy, also known as post-remission therapy, involves additional chemotherapy or a stem cell transplant to eliminate any residual leukemia cells and prevent relapse.

Genetic mutations in AML can influence prognosis and treatment decisions. Mutations in genes like FLT3, NPM1, and IDH1/2 are commonly tested.

Targeted therapies block specific pathways or proteins involved in leukemia cell growth. Examples include FLT3 inhibitors (e.g., midostaurin), IDH inhibitors (e.g., enasidenib), and BCL-2 inhibitors (e.g., venetoclax).

What is Acute Myelogenous Leukemia :

Acute Myelogenous Leukemia (AML) is a fast-growing cancer of the blood and bone marrow. It affects the myeloid cells, which are responsible for producing red blood cells, white blood cells, and platelets. In AML, the bone marrow produces abnormal myeloblasts (a type of white blood cell), red blood cells, or platelets. These abnormal cells can crowd out normal cells, leading to anemia, infection, or bleeding problems.

Causes of AML

The exact cause of AML is not always clear, but several risk factors and genetic mutations have been identified that can increase the likelihood of developing this disease:

Types of AML :

There are several subtypes of AML, each with distinct characteristics and treatment implications:

Symptoms of AML :

The symptoms of AML are often non-specific and can be mistaken for other common illnesses. They include:

Diagnosis of AML :

Diagnosing AML typically involves several tests and procedures:

Treatment Options for AML :

Treatment for AML is complex and depends on several factors, including the subtype of AML, the patient’s age, and overall health.

Cost of AML Treatment in India

The cost of AML treatment in India ranges from ₹5,00,000 to ₹35,00,000 (USD 6,000 to USD 42,000), depending on the treatment type (chemotherapy, targeted therapy, or stem cell transplant). Chemotherapy may cost around ₹18,000 per session (USD 231), while a bone marrow transplant costs ₹10,00,000 to ₹15,00,000 (USD 12,884 to USD 19,326).

Duration of Stay for Treatment in India

Treatment duration depends on the plan:

The overall stay may span several months based on individual response and treatment phases.

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