Dr Rahul Bhargava Haematologist

MBBS, MD, DM (Clinical Haematology)

Principal Director & Chief Hematology at Fortis Hospital

MBBS, MD, DM (Clinical Haematology)

Principal Director & Chief Hematology at Fortis Hospital

Erythrocytosis

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Frequently Asked Questions (FAQ) :

Erythrocytosis is a general term for an increased red blood cell count, while polycythemia vera is a specific type of primary erythrocytosis caused by a bone marrow disorder.

 

While erythrocytosis cannot always be cured, especially if it’s caused by a chronic condition, it can be effectively managed with treatments like phlebotomy and medications.

 

If left untreated, erythrocytosis can increase the risk of serious complications, including blood clots, strokes, or heart attacks. However, with proper treatment, these risks can be significantly reduced.

 

About Erythrocytosis

Erythrocytosis is a medical condition characterized by an increased number of red blood cells (erythrocytes) in the bloodstream. This excess can thicken the blood, leading to complications such as blood clots, strokes, or heart attacks. Erythrocytosis can be either primary or secondary, and identifying the underlying cause is crucial for effective treatment. Dr. Rahul Bhargava, a renowned haematologist, specializes in diagnosing and managing blood disorders like erythrocytosis.

Causes of Erythrocytosis

The causes of erythrocytosis can be varied, and it’s essential to identify the root cause for proper treatment. The common causes include:

  • Primary erythrocytosis (Polycythemia Vera): A rare bone marrow disorder that produces too many red blood cells.
  • Secondary erythrocytosis: Caused by external factors that stimulate red blood cell production, such as:
    • Chronic lung or heart disease
    • Living at high altitudes
    • Sleep apnea
    • Kidney disease
    • Tumors that produce erythropoietin
    • Smoking or use of certain drugs like anabolic steroids

Types of Erythrocytosis

Erythrocytosis can be classified into two major types:

  • Primary Erythrocytosis: Caused by an intrinsic bone marrow problem, where too many red blood cells are produced without any external triggers. Polycythemia Vera is the most common example.
  • Secondary Erythrocytosis: This type is due to conditions or environmental factors, such as living at high altitudes or certain medical conditions, that cause the body to produce more red blood cells.

Symptoms of Erythrocytosis

Many people with erythrocytosis may not experience symptoms, especially in the early stages. However, as the red blood cell count increases, common symptoms may include:

  • Headaches and dizziness
  • Fatigue or weakness
  • Shortness of breath
  • Blurred vision
  • High blood pressure
  • Itching, particularly after a warm shower or bath
  • Enlarged spleen (splenomegaly)

 

Diagnosis of Erythrocytosis

Diagnosing erythrocytosis typically involves a thorough medical history, physical examination, and a series of tests such as:

  • Complete Blood Count (CBC): To measure the levels of red blood cells.
  • Blood Oxygen Levels: To check oxygen saturation and identify secondary causes like lung disease.
  • Erythropoietin Levels: To assess if the body is producing excess erythropoietin.
  • Bone Marrow Biopsy: In cases of suspected Polycythemia Vera, a bone marrow biopsy might be required to confirm the diagnosis.

Treatment of Erythrocytosis

The treatment approach depends on the type and cause of erythrocytosis. The primary goal is to reduce the risk of complications like blood clots. Treatment options include:

  • Phlebotomy: Regular removal of blood to reduce red blood cell count and volume.
  • Medications: In some cases, medications like hydroxyurea may be prescribed to control the production of red blood cells.
  • Treating the Underlying Cause: For secondary erythrocytosis, treating the root cause (e.g., lung disease, sleep apnea) is essential for controlling the condition.
  • Aspirin: Low-dose aspirin may be recommended to reduce the risk of blood clotting.

Cost of Treatment and Stay in India

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