Ewing Sarcoma
Ewing Sarcoma
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Frequently Asked Questions (FAQ) :
Survival rates depend on the stage at which the cancer is diagnosed. When caught early, survival rates can be as high as 70-80%. However, if the cancer has spread (metastasized), the survival rate drops to around 30%.
No, Ewing Sarcoma is not typically passed down through families. It is caused by a genetic mutation that occurs in the cells after birth.
Although Ewing Sarcoma is more common in children and young adults, it can occur in adults as well.
Treatment duration depends on the stage of cancer and the treatment plan. Most treatments last several months, and rehabilitation may take additional time.
Introduction to Ewing Sarcoma
Ewing Sarcoma is a rare and aggressive form of cancer that primarily affects the bones or the soft tissues surrounding the bones. Most commonly found in children and young adults, Ewing Sarcoma can occur in any bone, but it typically arises in the pelvis, legs, or arms. It requires early diagnosis and aggressive treatment for the best possible outcome.
With advanced care and expert guidance from leading oncologists like Dr. Rahul Bhargava, patients have access to cutting-edge treatments, offering hope to individuals and families affected by this disease.
What is Ewing Sarcoma?
Ewing Sarcoma is part of a group of cancers known as Ewing Sarcoma Family of Tumors (ESFT). It was first described by Dr. James Ewing in the 1920s. This cancer affects bones and nearby tissues and can spread to other parts of the body.
Due to its rapid growth, early detection and treatment are critical in managing the disease.
Causes of Ewing Sarcoma
The exact causes of Ewing Sarcoma remain unclear, but genetic factors play a role. Unlike some cancers, lifestyle or environmental factors do not appear to contribute significantly to its development. However, a specific genetic mutation called the EWSR1-FLI1 fusion gene is often found in Ewing Sarcoma cells.
Factors that may increase the risk include:
- Age: Most common between ages 10-20.
- Gender: Males are slightly more likely to develop this cancer.
Types of Ewing Sarcoma
There are different types of Ewing Sarcoma, classified based on the location of the tumor:
- Bone Ewing Sarcoma: The most common form, it occurs in long bones like the femur, tibia, or humerus.
- Soft Tissue Ewing Sarcoma (Extraskeletal): This form arises in soft tissues rather than bones.
- Askin Tumor: A rare subtype found in the chest wall.
- Peripheral Primitive Neuroectodermal Tumor (PNET): A related tumor that can occur in soft tissues or bones.
Symptoms of Ewing Sarcoma
Early symptoms of Ewing Sarcoma can be mistaken for minor injuries or general pain, making early diagnosis challenging. If you or your child experiences any of the following symptoms, it’s essential to seek medical attention:
- Persistent bone pain or tenderness
- Swelling around the affected area
- Fever without an apparent cause
- Weight loss
- Fatigue or lethargy
- Fractures with minimal trauma
Diagnosis of Ewing Sarcoma
Accurate and timely diagnosis is vital for effective treatment. Dr. Rahul Bhargava and his team use a range of diagnostic tools to identify Ewing Sarcoma:
- Physical Examination: A thorough examination of the affected area.
- Imaging Tests:
- X-rays: To detect bone abnormalities.
- MRI or CT scans: For detailed images of soft tissue and bone.
- Bone Scans: To see if the cancer has spread to other bones.
- Biopsy: A small tissue sample is taken from the tumor and examined under a microscope to confirm the diagnosis.
- Genetic Testing: To detect the specific genetic mutation (EWSR1-FLI1 fusion gene) associated with Ewing Sarcoma.
Ewing Sarcoma Treatment Options in India
Dr. Rahul Bhargava provides a multi-disciplinary approach to treating Ewing Sarcoma. Treatment plans are personalized based on the stage of cancer, location, and overall health of the patient. The main treatment options include:
- Chemotherapy: The first line of treatment, chemotherapy, aims to shrink the tumor before surgery and target any cancer cells that may have spread.
- Surgery: Surgical removal of the tumor is often necessary after chemotherapy. In some cases, limb-sparing surgery can be performed, avoiding amputation.
- Radiation Therapy: Used when surgery is not possible or in combination with chemotherapy to destroy remaining cancer cells.
- Targeted Therapy: Innovative treatments that focus on specific cancer cell pathways and mutations.
- Stem Cell Transplant: For advanced cases, a stem cell transplant may be recommended to restore bone marrow after intensive chemotherapy.
Cost of Treatment and Stay in India
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