Dr Rahul Bhargava Haematologist

MBBS, MD, DM (Clinical Haematology)

Principal Director & Chief Hematology at Fortis Hospital

MBBS, MD, DM (Clinical Haematology)

Principal Director & Chief Hematology at Fortis Hospital

Leucocytosis

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Frequently Asked Questions (FAQ) :

A: No, leucocytosis can be caused by many conditions, including infections, inflammation, or stress. However, in some cases, it can indicate a bone marrow disorder like leukemia.

 

A: While you cannot always prevent leucocytosis, maintaining a healthy lifestyle, managing infections promptly, and reducing stress can help minimize risk.

 

A: The severity of leucocytosis depends on the underlying cause. Infections or stress-induced leucocytosis are often temporary and resolve with treatment, but bone marrow disorders like leukemia require more intensive care.

 

About Leucocytosis

Leucocytosis refers to an abnormally high number of white blood cells in the bloodstream. While white blood cells are essential in fighting infections, an increase in their count can indicate an underlying issue such as an infection, inflammation, or even a more severe condition like leukemia.

White blood cells (WBCs) help protect the body from infections and are part of the immune system. Normally, a WBC count ranges between 4,500 and 11,000 per microliter of blood, but in cases of leucocytosis, this count exceeds the normal range.

Causes of Leucocytosis

Several factors may cause leucocytosis, including:

  • Infections: Bacterial, viral, or fungal infections can trigger the body to produce more white blood cells to fight off the infection.
  • Inflammatory diseases: Conditions like rheumatoid arthritis or inflammatory bowel disease can increase white blood cell production.
  • Bone marrow disorders: Certain bone marrow conditions, including leukemia, can lead to leucocytosis.
  • Stress or physical trauma: Injury, surgery, or stress can cause a temporary increase in white blood cell count.
  • Medications: Some medications, such as corticosteroids, can increase white blood cell production.

Types of Leucocytosis

Leucocytosis can be categorized based on the type of white blood cell that is elevated:

  1. Neutrophilia: An increase in neutrophils, often caused by infections or inflammation.
  2. Lymphocytosis: Elevated lymphocytes, which can occur due to viral infections or certain cancers like leukemia.
  3. Monocytosis: Higher levels of monocytes, typically seen in chronic infections or inflammatory conditions.
  4. Eosinophilia: Increased eosinophils, often associated with allergies, parasitic infections, or autoimmune diseases.
  5. Basophilia: An elevation in basophils, which is less common but can be linked to leukemia or other bone marrow disorders.

Symptoms of Leucocytosis

Leucocytosis itself may not present specific symptoms, but the underlying condition causing the elevated white blood cells often does. Common symptoms include:

  • Fever and chills
  • Fatigue or general weakness
  • Shortness of breath
  • Dizziness or lightheadedness
  • Unexplained weight loss
  • Swollen lymph nodes or spleen
  • Infections or frequent illnesses

Diagnosis of Leucocytosis

To diagnose leucocytosis, Dr. Rahul Bhargava conducts a series of tests, including:

  • Complete Blood Count (CBC): This test measures the levels of different blood cells, including white blood cells, and determines if your WBC count is elevated.
  • Bone Marrow Biopsy: In cases where a bone marrow disorder is suspected, a bone marrow biopsy may be performed.
  • Peripheral Blood Smear: A blood smear helps analyze the shape and appearance of blood cells, providing clues about potential causes of leucocytosis.
  • Other Diagnostic Tests: Depending on the suspected cause, additional tests such as imaging, genetic tests, or tests for infections may be conducted.

Treatment of Leucocytosis

The treatment of leucocytosis depends on the underlying cause:

  • Infection management: Antibiotics, antivirals, or antifungal medications are prescribed if the leucocytosis is due to an infection.
  • Medications for inflammation: Anti-inflammatory drugs may be used to treat conditions like rheumatoid arthritis or inflammatory bowel disease.
  • Leukemia treatment: If leucocytosis is caused by leukemia, treatment may include chemotherapy, radiation therapy, or stem cell transplant.
  • Lifestyle adjustments: In some cases, reducing stress and making lifestyle changes can help manage leucocytosis.

Cost of Treatment and Stay in India

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