Dr Rahul Bhargava Haematologist

MBBS, MD, DM (Clinical Haematology)

Principal Director & Chief Hematology at Fortis Hospital

MBBS, MD, DM (Clinical Haematology)

Principal Director & Chief Hematology at Fortis Hospital

Lymphocytosis

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Frequently Asked Questions (FAQ) :

Lymphocytosis itself is not dangerous, but the underlying cause may be serious, such as infections or blood cancers. Early diagnosis is key.

 

Lymphocytosis refers to high lymphocyte levels, while leukemia is a type of blood cancer that can cause abnormal lymphocyte production. A detailed diagnosis will differentiate between the two.

 

If lymphocytosis is caused by a temporary infection, it can resolve on its own once the infection is treated. However, persistent lymphocytosis requires medical evaluation.

 

About Lymphocytosis

Lymphocytosis is a condition characterized by an increase in the number of lymphocytes in the blood. These white blood cells are critical to your body’s defense mechanisms, but an unusually high count may indicate an underlying problem. Lymphocytosis is often seen in response to infections, but it can also signal more complex medical conditions like leukemia or lymphoma.

Causes of Lymphocytosis

There are several causes of lymphocytosis, including:

  • Viral infections (such as mononucleosis, cytomegalovirus)
  • Bacterial infections (like tuberculosis, pertussis)
  • Chronic inflammatory conditions (like Crohn’s disease or ulcerative colitis)
  • Blood cancers (like chronic lymphocytic leukemia or lymphoma)
  • Autoimmune disorders (such as lupus)
  • Reactions to medications

Types of Lymphocytosis

There are two primary types of lymphocytosis:

  1. Reactive Lymphocytosis: Occurs as a response to infections or other temporary immune system triggers.
  2. Clonal Lymphocytosis: This is usually associated with blood cancers and involves the production of abnormal lymphocytes.

Symptoms of Lymphocytosis

Lymphocytosis itself often has no specific symptoms, but the underlying cause may produce noticeable signs, such as:

  • Fever or persistent infections
  • Unexplained weight loss
  • Fatigue or weakness
  • Enlarged lymph nodes
  • Night sweats
  • Easy bruising or bleeding

If you experience any of these symptoms, it is crucial to seek medical evaluation.

Diagnosis of Lymphocytosis

To diagnose lymphocytosis, a healthcare professional will typically perform:

  • Complete Blood Count (CBC): This test measures the number of lymphocytes and other blood cells.
  • Blood Smear: A closer look at your lymphocytes to assess abnormalities.
  • Bone Marrow Biopsy: In cases where a blood disorder is suspected.
  • Flow Cytometry: Used to analyze lymphocytes in detail for signs of malignancy.

Accurate diagnosis is the first step toward determining the best course of treatment.

Treatment for Lymphocytosis

Treatment for lymphocytosis depends on its underlying cause. Common treatment options include:

  • Antibiotics or antiviral medications: For infections causing lymphocytosis.
  • Corticosteroids: To reduce inflammation in autoimmune conditions.
  • Chemotherapy or immunotherapy: For blood cancers like leukemia or lymphoma.
  • Observation: In some cases, especially for mild lymphocytosis, no treatment may be necessary if it resolves on its own.

Cost of Treatment and Stay in India

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